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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T27985 | MC-70 | MC70,MC 70 | |
MC-70 is a potent P-glycoprotein (P-gp) inhibitor (EC50 = 0.69 μM). | |||
T69897 | MC-70 hydrochloride | ||
MC-70 hydrochloride is a potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively). | |||
T69896 | Sabarubicin | MEN 10755 | |
Sabarubicin, a doxorubicin disaccharide analogue, exhibits pronounced antitumor activity and surpasses doxorubicin in effectiveness as a topoisomerase II poison, promoting DNA fragmentation at reduced intracellular conce... |